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The body’s own immune system can sometimes mistakenly attack healthy tissues, including nerves. Autoimmune disorders like rheumatoid arthritis or Guillain-Barré syndrome can involve inflammation and damage to the nerves, which can consequently lead to tingling sensations in the hands and other parts of the body. These conditions often present with a broader range of symptoms, such as joint pain in the case of rheumatoid arthritis or muscle weakness in Guillain-Barré syndrome.
Proper blood flow is essential for the health and function of all tissues, including nerves. Poor circulation can therefore be a cause of tingling in the hands. Conditions like Raynaud’s phenomenon, which causes the small blood vessels in the fingers and toes to narrow in response to cold or stress, can lead to a temporary reduction in blood flow, resulting in tingling and numbness. Other circulatory issues, such as the buildup of plaque in the arteries (atherosclerosis), can also restrict blood flow to the hands and contribute to similar symptoms.