Another sign that should not be overlooked is the presence of blood in the stool . While this symptom can be related to other benign conditions, it always requires a proper medical evaluation. Frequent abdominal pain , bloating, or constant discomfort that interferes with daily life may also occur. In some cases, people experience unintentional weight loss , accompanied by persistent fatigue or general weakness—signs that may be associated with low blood iron levels and the development of anemia .